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Thyroid hormones are essential for normal development, growth, and metabolism. We used a Monte Carlo maximum likelihood (MCML) approach to estimate the effectiveness of meningococcal vaccines, based on stochastic simulations of a dynamic model for meningococcal transmission and vaccination. Carotid intima-media thickness (IMT) was a marker of subclinical CVD.

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Reaction kinetics of waste sulfuric acid using H2O2 catalytic oxidation. In the direct exposure experiments, PVP-AgNP had no effect on germination while 40 mg Ag L(-1) GA-AgNP exposure significantly reduced the germination rate of three species and enhanced the germination rate of one species.

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Use of direct immunofluorescence in the detection of canine parvoviruses in tissue culture However, in isolated ocular forms, histopathological examination is necessary. Reading words for meaning relies on orthographic, phonological and semantic processing. We also use compressibility as a new quantitative phenotype and find that the behaviour of wild-isolated strains of C. The stem cells that maintain and repair the postnatal skeleton remain undefined.

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The foetal valproate syndrome is a complex of symptoms which is probably underdiagnosed and should be considered in the diagnostic evaluation program for children with developmental delay who are born of mothers with epilepsy. Importance of angle correction in the measurement of blood flow velocity with transcranial Doppler sonography. In long existing cases only a weak or negative fluorescence was observed in this material, expressed by light microscopy as hyaline transformation. Nanocrystalline NaZSM-5 zeolites with systematically varied particle sizes (15, 60, and 200 nm) were functionalized with organosilanes. Interdisciplinary approaches, combining quantitative physical modeling with cell biology, are of growing interest to journal editors, funding agencies, and hiring committees.

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Acute disseminated encephalomyelitis causes multifocal demyelination in the central nerve system. Between 10(-7) and 10(-6)M, PGE1 induces an increase of cAMP content, significantly more important in SHR, which persists in the presence of isobutylmethylxanthine (IBMX) 10(-5)M. Finally, expression of mutated forms of p21 ras did not abrogate the sensitivity of phospholipase C activation to pertussis toxin. Furthermore, current treatment regimens are messy, time consuming and, in some instances, ineffective, leading to a high level of non-compliance.

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Here we examine the role of the IRF-1 in the response of ovarian cancer cells to the front-line chemotherapeutic drug cisplatin (CDDP). Previously, we demonstrated that indoxyl sulphate (IS), a uraemic toxin, induced aortic calcification in hypertensive rats. injection of L-dopa, of which the tissue concentration declined monoexponentially. The direct anterior approach (DAA) for total hip arthroplasty (THA) is typically performed in the supine position using a specially designed operating room table, which makes this approach more accessible to orthopedic surgeons. The prognostic usefulness of coronary CTA findings of coronary artery disease in relation to XECG findings has not been explored systematically.

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We report herein the occurrence of a drug reaction with eosinophilia and systemic symptoms (DRESS) secondary to intake of this drug. A total of 38 constituents were identified in TSC sample based on the comparison of retention time and UV spectra with authentic compounds as well as by summarized MS fragmentation rules and matching of empirical molecular formula with those of published components. The computed electronic structures suggest that the most stable structure is metal while the meta-stable structure of BLG is a semiconductor with an indirect band gap (0.32 eV at the level of PBE functional and 0.81 eV at the level of HSE06). Preparation and some properties of a polyethyleneimine-agarose metal adsorbent.

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THE OSTEOGENIC POWER OF PERIOSTEUM: WITH A NOTE ON BONE TRANSPLANTATION: AN EXPERIMENTAL STUDY. Non-surgical therapy for patients with advanced non-small cell lung cancer.

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The Z0011-study, a landmark randomised controlled trial (RCT) challenged the benefits of complete axillary lymph node dissection (ALND) compared with sentinel lymph node dissection only (SLND) in breast cancer patients with positive sentinel nodes. We demonstrate that this selective regulation of RNA polymerase II phosphorylation state exists within human cells, consistent with in vitro assays. Infiltration treatment for gonarthrosis is among the most widely used techniques in orthopaedic practice.

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Hepatocyte proliferation critically contributes to the process of liver regeneration (LR), which is regulated by various cytokines and growth factors. Body weight, ascites, and Child-Pugh score were assessed at baseline, at 2 months, and after a mean 8.8-month follow-up interval. Consideration of cardiovascular risk is needed when prescribing antipsychotics, as is close monitoring for metabolic changes during treatment. A retrospective epidemiological study was conducted in the emergency departments of Rennes, Lorient and Saint-Brieuc over a period of three months.

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PTHrP is a unique stretch-induced endogenous detrusor relaxant that functions via PTH1R. This produces context-dependent repetition effects, which are functionally similar to episodic repetition effects. The results of this study revealed that CK20, CD44, P53 and Ki67 are useful in distinguishing CIS from reactive and normal samples. Biomimetic scaffolds that promote regeneration and resist proteolysis are required as a tissue engineering solution to repair or replace a broad range of diseased tissues. Modified basal osteotomy combined with osteogenic distraction (Hemi-Wing distraction) for correction of facial asymmetry: A new technique.

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Slow IPSP and the noradrenaline-induced inhibition of the cat sympathetic preganglionic neuron in vitro. Infraclavicular metastasis to the parotid is rare but should not be overlooked particularly in patients who present with coexisting conditions, or when cytological findings are atypical.

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We also aimed to determine the severity of lesions and find possible correlations, and to seek a relationship of these observations with light microscopical and clinical findings. Though radiotherapy (56 Gy whole brain irradiation) was conducted after the sixth operation, multiple tumors recurred and clinical symptoms and signs deteriorated gradually and he finally died September 9, 1989. High incidence of intracranial bleeding in factor V-deficient patients with homozygous F5 splicing mutations.

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This work suggests that approaches to target the RACK1/PP2A complex are a viable option to regulate PP2A activity and identifies a novel potential therapeutic target in the treatment of breast cancer. Scleral biomechanical weakness and thinning is known to be one of the main factors in the pathogenesis of progressive myopia. Cholinergic denervation in a pure multi-infarct state: observations on CADASIL. Medical management with antiplatelet (AP) and statin therapy is recommended for nearly all patients undergoing vascular surgery to reduce cardiovascular events. Presumed endometriotic sites were observed in 164 patients operated on under the clinical suspicion of endometriosis.

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In this study, we aimed to evaluate the influence of diet-induced obesity on IL-6 deficiency-induced bone remodeling abnormality. Isolation and Characterization of a New Thermoalkalophilic Lipase from Soil Bacteria. Infections and sterile injuries represent two common challenges imposed on the CNS that require a prompt immune response. In our experiments, six species of bacteria were used to demonstrate the capability of the confocal LTRS in the identification and discrimination between the diverse bacterial species at various growth conditions. The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression.

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Post-cardiac arrest (CA) patients have a large cerebral penumbra at risk for secondary ischemic damage in case of suboptimal brain oxygenation during ICU stay. A flow cell optosensor for lead based on immobilized gallocynin in chitosan membrane. This study tested the hypothesis that adenosine A(1) and A(2A) receptors in the prefrontal cortex contribute to the regulation of behavioral and cortical arousal. Exploratory studies using a racemic version of the catalyst were also conducted. Ectoderm from the proximal anterior border of the limb induces high expression of both GHox-7 and GHox-8, while ectoderm from the proximal posterior border does not induce expression of either gene.

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They show a strong narrow absorption peak that characterizes a type II confinement in accordance with theoretical predictions. Hypoxia initiates signaling and transcriptional alterations to promote survival of cancer cells and generation of cancer stem cells (CSCs) that have self-renewal and tumor-initiation capabilities. Although the biological activity of the majority of alternatively spliced isoforms and their contribution to cancer biology has yet to be determined, their elucidation will have a large impact on therapeutic strategies for cancer. The region between the epidermis and the surface of the overlapping part of scales has been studied in two cichlid teleosts using transmission electron microscopy. A greater inhibition was observed with both antagonists administered together.

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Ethnicity may have to be considered an additional outcome variable in fertility studies. SEX DIFFERENCES IN ACHIEVEMENT MOTIVE IN MATHEMATICS AS RELATED TO CULTURAL CHANGE.

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Characterization of anti-myocardial autoantibodies in Japanese patients with dilated cardiomyopathy. She was discharged on postoperative day 21 without any cardiac events following early introduction of cardiac rehabilitation.

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