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Topictal (Topiramate)

Topictal is the brand name of Topictal, an anticonvulsant drug used to prevent seizures and reduce the frequency of migraines. While its exact mechanism of action is unknown, studies suggest Topictal might alter the production or action of neurotransmitters in the brain, suppressing the abnormal activity of the nerves in the brain that cause seizures or preventing the abnormal activity from spreading to other nerves. Other research has suggested that it might suppress the nerves directly, thereby making them less likely to fire. The Food and Drug Administration (FDA) approved Topictal to treat seizures in 1996.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

Similar Products:
Panzo, Amoxy, Auxxil, Amoxicure, Flomax, Exomax, Zargus, Vadiral, Valtrex, Emez, Tetracycline, Azithromycin, Senexon, Auram, Donaren, Lanzor, Novitropan, Krobicin, Epsin, Sebrane, Carbamazepine, Ketipinor, Barole, Bicalutamide, Reskuin, Viralex,

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We developed RLooM, a web application for homology-based modeling of RNA loops utilizing template structures extracted from the PDB. A unit cell pattern with gradient edges is discussed, and variable resistor and variable capacitor are introduced to fully utilize its characteristic of multi-resonances. Thus, we decided and performed a one-stage mandibular angle ostectomy with fracture management.

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The last two decades have seen technological developments that have led to more accurate delivery of radiation therapy (RT), which has resulted in clinical gains in many solid tumors. The eruption of the respective bicuspids took place earlier than expected. Despite increased cardiovascular disease (CVD) risk, rheumatoid arthritis (RA) patients often lack CVD preventive care.

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Chemotaxonomic perspectives of the Paracaryum (Cynoglosseae, Boraginaceae) taxa based on fruit fatty acid composition. Evaluation of drug usage and expenditure in a hospital diabetes clinic. We report a case of a 25-y-old man who presented to our department with diffuse interstitial pulmonary infiltrates and slightly enlarged mediastinal lymph nodes as determined by computed tomography. Effects of different loading doses of dexmedetomidine on bispectral index under stepwise propofol target-controlled infusion. It is concluded that the ATP/ADP antiporter is somehow involved in the uncoupling effect caused by low concentrations of palmitate and, partially, of dinitrophenol, whereas uncoupling produced by FCCP and gramicidin is due to their action on the phospholipid part of the mitochondrial membrane.

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Mitochondrial Dysfunction Contributes to Hypertensive Target Organ Damage: Lessons from an Animal Model of Human Disease. Given the exploratory and preliminary nature of the study, continued research is needed to further examine the relationship between EMS, EDs, and substance use.

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coli isolates attached better to both cell lines than Salmonella isolates. Data collection on demographics, antithrombotic usage, and thrombotic and bleeding episodes from January-June 2001. Surgical approaches to the elbow joint that dissociate the triceps from the olecranon have distinct disadvantages. The PWV ratio between the two groups was significantly different and correlated positively with duration of diabetes and systolic blood pressure (SBP). Height reduction in the motion segment leads to abnormal strains in one type sooner than in the other, which can be normalized by slight flexion.

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In this work, polydimethylsiloxane (PDMS) surfaces were modified with epidermal growth factor (EGF) to improve the growth of corneal epithelial cells. Plasmodium vivax malaria recurrence according to the use of primaquine: analysis of longitudinal descriptive studies The establishment of sensory and motor blockade of individual nerves was similar to 20-gauge short and blunt bevel needle under ultrasound guide with no neurological adverse events.

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Anti-ganglioside GM1 antibodies were moderately elevated in this patient. Glial tumors seem to be able to create a favorable environment for the invasion of neoplastic cells into the cerebral parenchyma when they interact with the extracellular matrix via cell surface receptors. This raises the exciting possibility that in conditions of hyperactive synaptic pruning, as supposed in schizophrenia, the inhibitory action of minocycline turns into a beneficial effect, with relevance for early therapeutic interventions.

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Importantly, VAD inhibits the incorporation of the repressive histone variant H2A.Z at INK4 gene promoters in senescent cells. LPP3 was localized to cell-cell contact sites and was missing in non-contact sites to which LPA-induced actin stress fibre formation mediated by LPA6 was restricted. In addition, we examined how RSTN might affect neuropeptide Y (NPY)-induced feeding, as studies have shown that rat RSTN can interfere with the NPY system. Acoustic-distortion products were elicited at 1, 2.5, and 4 kHz by equilevel primaries at 65, 75, and 85 dB SPL, while f2/f1 ratios were varied in 0.02 increments from 1.01-1.41 (4 kHz), 1.01-1.59 (2.5 kHz), or 1.01-1.79 (1 kHz). It is, however, not possible to consider anyone free of the condition, even if the aortic diameter is normal, especially at a younger age.

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Expression of Slit3/Robo signal pathway in mouse aortic smooth muscle cell and its impact on proliferation and migration Twenty-four patents disclosed in the period of 2000-2015 were covered in this review. POLYPLOIDY IN THE MEXICAN AXOLOTL (AMBYSTOMA MEXICANUM) RESULTING FROM MULTINUCLEATE OVA. Immunoglobulin G infusion used in the prophylaxis of the septic complications achieved high titers of cytomegalovirus-specific immunoglobulin G, as well as the subsets immunoglobulin G1 and immunoglobulin G3 which are also active against cytomegalovirus. The 13C-urea breath test has been validated in children of different age groups in a significant number of infected and noninfected children in several countries and, thus far, is the only noninvasive test that fulfills sensitivity and specificity quality standards.

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Limitations of dynamic contrast-enhanced MRI in monitoring radiation-induced changes in the fraction of radiobiologically hypoxic cells in human melanoma xenografts. We discuss these findings in terms of a working model, where ginkbilobin can activate actin-dependent cell death.

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Patients missing baseline information or those lost to follow-up were excluded. Numbers of ammonia oxidisers in the lakewater were small throughout the year, and tangential-flow concentration was required to obtain meaningful estimates of most probable numbers. Based upon our observation that RNA silencing of fos-related antigen 1 (Fra-1) inhibited c-met expression in rat mesotheliomas (1), we hypothesized that Fra-1 was a key player in HGF-induced proliferation in human MMs. Ninety-three consecutive patients with pituitary adenomas underwent transphenoidal pituitary operations at Gulhane Military Medical Academy from January 1996 to October 2007. Hysteresis behavior of amphiphilic model peptide in lung lipid monolayers at the air-water interface by an IRRAS measurement.

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Infectious agents are known to contain Hsp70, which is markedly immunogenic and can elicit a strong immune response. Head and neck diseases in children and adolescents present special diagnostic and differential diagnostic challenges to ENT surgeons as well as to radiologists.

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Age-standardized mortality rates and age-specific rates of lung cancer in China were estimated for the periods 1973 to 1975, 1990 to 1992, and 2004 to 2005 using data from 3 National Death Surveys. Cutaneous polyarteritis nodosa following hepatitis B vaccination Thus, VS2 can have better structural stability in the cycles of charging and discharging.

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Soft tissue augmentation was done first using a new tunnel technique with ADM allograft. Minimizing glycemic variability in type 2 diabetic patients, especially postprandial glucose excursions following breakfast, may be an important aspect of glucose management.

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Immunocytochemical detection of estrogen receptor-alpha in the female rabbit forebrain: topography and regulation by estradiol. Finally, the possibility that G-quadruplexes form in the cells was demonstrated by using of L1BOD-7OTD. Negative correlation was observed between FSH and glutathione peroxidase. Two examiners evaluated independently 42 sites adjacent to tooth-colored restorations using visual inspection (ICDAS-CARS), radiographic examination, and QLF. Theoretical study on the gas-phase reaction mechanism between nickel monoxide and methane for syngas production.

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Whether the role of serotonin is related to memory and/or behavioral or emotional aspects remains an important question. In this work, design and fabrication of micro-gas-sensors, polymerization and deposition of poly(pyrrole) thin films as sensitive layer for the micro-gas-sensors by electrochemical processing, and characterization of the polymer films by FTIR, X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM), are reported.

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In yeast, the formation of this modified nucleoside is catalyzed by the essential tRNA (m1A58) methyltransferase, a tetrameric enzyme that is composed of two types of subunits (Gcd14p and Gcd10p). According to the literature, no such study has been performed in this group. A CASE OF DIABETES MELLITUS WHICH SHOWED HYPERSENSITIVE REACTION TO DEPOT INSULIN Novel compound heterozygous nonsense mutations in the hairless gene causing atrichia with papular lesions.

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A fast training algorithm is developed for two-layer feedforward neural networks based on a probabilistic model for hidden representations and the EM algorithm. We discuss the pathogenic mechanism in which, besides the involvement of several central mechanisms, one can also incriminate some peripheral ones (probably the change of interstitial pressure at the nerve and/or muscle level). SBUR was not different statistically between various molecular subtypes.

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Scar treatment in laser age: appropriate education and expectations are essential. Identification of diabetes, heart disease, hypertension and stroke in mid- and older-aged women: Comparing self-report and administrative hospital data records. We diagnosed her as having juvenile myoclonus epilepsy and initiated sodium valproate monotherapy, which relieved the symptoms. No subjects had impairments of kicking, reaching, pinching, or speech. Change in the dosage strength along the radiation beam axis in x-ray apparatus

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In the testis CRABP was found in the seminiferous tubuli with Sertoli cells and the spermatogonia most intensely stained. The CT recognition of bilateral spondylolysis of L3 suggested the possibility of a mobile posterior arch of L3 and associated synovial herniation. Peri selectivity of the electrocyclization of 1-aryl- and heteroaryl-substituted (1Z,3Z)-1,3,5-hexatrienes, obtained by Ru-catalyzed linear coupling of 1,6-diynes to Z-propenyl(hetero)arenes, can be efficiently modulated depending on the aromaticity of the (hetero)arene: 1,3,5-hexatrienyl(hetero)arenes give 8pi e- electrocyclization with the exception of 1,3,5-hexatrienylbenzenes, which give 6pi e- electrocyclization.

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Therefore, we set this work to explore IL-5 as a plasma biomarker for early subclinical atherosclerosis, as determined by measures of baseline severity and change over time of carotid intima-media thickness (cIMT). The diffusion of cardiac catheterization laboratories in Italy has been increasing in the last decade, often without a rational planning process evaluating costs, safety, concentration and case loads. The impact of financial constraints and incentives on professional autonomy.

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Polyethylenimine (PEI) is a cationic polymer capable of delivering DNA molecules into cultured mammalian cells as charge complexes. Uvulopalatopharyngoplasty (UPPP) has been a popular surgical method for treating obstructive sleep apnea syndrome since it was introduced in the early 1980s. Here the value and usefulness of a methodology that uses walk-in field cages with host trees to assess, under semi-natural conditions, mating compatibility within these complexes is reviewed, and the same methodology to study the role of chemical communication in pre-mating isolation among Anastrepha fraterculus populations is used.

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Each microRNA can putatively target the expression of hundred mRNAs and consequently impact on many cellular functions. Therefore, clinical trials investigating new treatments in ADHD should include assessments at follow-up as their primary endpoint rather than assessments at outtake. Nanofocusing of terahertz wave in a tapered hyperbolic metal waveguide. Cilia are used effectively in a wide variety of biological systems from fluid transport to thrust generation. The intensive care unit psychosocial care scale: Development and initial validation.

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Improvement in cystic fibrosis (CF) outcomes over the past 50 years has been dramatic. Although remote from pollution sources, the Faroe Islands show high concentrations of POPs in human milk, particularly PCBs, but also PBDEs. They evolve through gene duplication, subfunctionalization in expression domain and divergence of duplication products, largely in CTT residues that mediate interactions with other proteins.

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We performed a retrospective analysis of the Nationwide Inpatient Sample for the year 2008. NIH to require balanced sex representation in animal and cell studies. Role of a specific choline pool in sphingomyelin synthesis in rat heart. The labio-lingual asymmetry which characterizes this tooth is initiated at the cap stage and increases further during the cap to bell transition (ED14 to ED16) when histogenesis of the enamel organ proceeds.

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After the recurrence of ventricular tachycardia the patient was submitted to electrophysiological study revealing a re-entrant circuit at the level of the medium segment of interventricular septum, successfully treated with transcatheter ablation. Water insoluble nickel compounds have been shown to enter cells by phagocytosis and are contained in cytoplasmic vacuoles, which are acidified thus accelerating the dissolution of soluble nickel from the particles. The translation arrest is released when SRP interacts with its receptor on the ER membrane. Update: adverse events following smallpox vaccination--United States, 2003.

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We describe in this report an economic approach to construct a multiplexed capillary electrophoresis (CE) system with optic-fiber UV detection. Effect of the molecular architecture on the thermosensitive properties of chitosan-g-poly(N-vinylcaprolactam). The performance of different transducer shapes and the influence of the thickness and length of the beam element in the transducer has been studied. The first non-stereoselective stage of the assay (PRP-1 column) separates and quantitates parent drug and metabolites. Antinociceptive and antipyretic activities of Pongamia pinnata leaves.

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Sequence-independent characterization of viruses based on the pattern of viral small RNAs produced by the host. Autothermal catalytic partial oxidation of glycerol to syngas and to non-equilibrium products. The use of cold resection techniques and EMR has increased over time. Of four anti-rabbit CD18 Mabs tested, only one, L13/64, has been shown to be capable of inhibiting the adhesion of fMLP-stimulated neutrophils to gelatin coated plastic and the homotypic aggregation of PMA-stimulated T cells, both of which assays have been shown to be CD18-dependent. Timed urine samples were collected precaffeine (basal) and at 1, 2, and 3 h post-caffeine.

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Draining the bladder with SPT only is a feasible option in patients undergoing RALP. PD patients who were diagnosed with PD prior to age 60 and were followed at an academic movement disorders center were consecutively invited to participate in a survey concerning their employment history and experience with SSDI. The efficacy of this liposomal amphotericin B formulation appears to be related both to improved tissue penetration in the lungs, brain, kidneys, liver and spleen along with sustained bioactivity of therapeutic drug levels in these target tissues.

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Effect of induced body condition score differences on physiological response, productive and reproductive performance of Malpura ewes kept in a hot, semi-arid environment. The direction, magnitude and timing of climate sensitivity varied markedly among organisms within taxonomic and trophic groups. However, images acquired 6 h after gadofosveset injection have significantly better diagnostic dexlansoprazole equivalent dose lansoprazole generic prevacid information endpoints and contrast enhancement. Local RAS is crucially involved in basic physiological processes like ontogenesis and cell proliferation as well as pathophysiological conditions such as inflammation and tissue fibrosis.

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Sixteen patients had surgical release of the extensor tendon origin along with excision of the lateral epicondyle ridge. The reason why no RRF was found in the denervated muscle is that the ischemic state in the denervated muscles is relieved by immobilization after denervation. The addition of isoproterenol resulted in an increased rate of internalization of the receptor-BRK2-anti-IgG-gold complex. Identification of the lesion in the stimulatory treatment for thrush in women diflucan fluconazole GTP-binding protein of the uncoupled S49 lymphoma.

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Knowledge about retinal photoreceptor signal transduction and the visual cycle required for normal eyesight has increased exponentially over the past decade. SO-CALLED COR TRIATRIATUM DEXTRUM: REVIEW OF THE LITERATURE AND REPORT OF A CASE. Assessing health care use and cost barambo tiramisu ingredients consequences of a new screening modality: the case of digital mammography.