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Functional, cellular, and molecular characterization of the angiogenic response to chronic myocardial ischemia in diabetes. To study the efficacies of intratympanic prednisolone and dexamethasone injection for the subjective tinnitus. Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells. In November 2000, the National Aeronautics and Space Administration (NASA) and its partners in the International Space Station (ISS) ushered in a new era of space flight: permanent human presence in low-Earth orbit.

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A study of the effect of Bacillus thuringiensis serotype H14 (subspecies israelensis) delta endotoxin on Musca larva. In the interim, another everolimus-eluting-stent had been placed on the same lesion. Influence of habitual dietary fibre intake on the responsiveness of the gut microbiota to a prebiotic: protocol for a randomised, double-blind, placebo-controlled, cross-over, single-centre study.

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We report here that the laminin receptor, integrin alpha 6, is down-regulated in the dorsal neural tube when CNC cells emigrate, this process is mediated by cVICKZ, and integrin alpha 6 mRNA is found in VICKZ ribonucleoprotein complexes. A Recursive Partitioning Method for the Prediction of Preference Rankings Based Upon Kemeny Distances. Interactions of troponin I and its inhibitory fragment (residues 104-115) with troponin C and calmodulin. Tricyclic antidepressants dosage and depressed elderly inpatients: a retrospective pharmaco-epidemiologic study

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The effectiveness and safety of treatments used for polycystic ovarian syndrome management in adolescents: a systematic review and network meta-analysis protocol. Symptomatic patients should be evaluated initially with posteroanterior and lateral chest radiographs. As these diagnostic methods improve, the ultimate hope is to eliminate biopsy in patients without cancer.

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Recently it was shown that large hip circumference (HC), measured once, was protective against total and cardiovascular disease (CVD) mortality in women but that gain or loss in HC was unrelated to these outcomes. Different benign and malignant diseases may present such a symptom.

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This subsequent study was designed to assess the effect of WP on heat shock protein-72 (Hsp72) and keratin16 (Krt16) expression during wound healing in diabetic rats. Episcleral application of mitomycin-C (MMC) during glaucoma surgery hinders the post-operative wound healing but may lead to side effects to the ciliary body.

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Contributions of vascular, endocrine, and neurologic system alterations result in this disturbing condition, but a detailed analysis of all the parameters was not found in any individual study. At 1 year, a strategy of PLDD, followed by surgery if needed, resulted in noninferior outcomes compared with surgery. Conformational restriction is a useful strategy for studying the relationship between the molecular topology and biological activity of compounds.

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Both therapies were effective in the treatment of intrabony defects in AgP patients, and no statistically significant differences between them could be demonstrated, possibly as a result of the differing degrees of membrane exposure at the GTR sites. Hepatic carcinoma-associated fibroblasts enhance immune suppression by facilitating the generation of myeloid-derived suppressor cells. One very conservative mutation, leucine 183 to isoleucine, conferred nearly wild-type levels of Snf1 kinase function in the absence of the Snf4 protein. We purified the factor responsible for this novel depolymerizing activity using biochemical fractionation and a visual activity assay and identified it as XMAP215, previously identified as a prominent MT growth-promoting protein in Xenopus extracts.

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Phosphate-binding effects of sucralfate in patients with chronic renal failure. Over 12 weeks, participants received supervised group-exercise therapy or a home-based exercise-therapy program. Hormonal status was modified by surgical adrenalectomy, followed by subsequent replacement therapy with corticosterone, and by chronic corticosterone treatment of intact rats, followed by its withdrawal. Simultaneous determination of penicillin G and its major metabolites in blood using ultra performance liquid chromatography-tandem mass spectrometry Na2SeO3 supplementation in the ageing medium could protect aged erythrocyte ghosts from decreases in lipid fluidity, Na, K-ATPase activity, and sensitivity to ouabain.

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The PLNR contributes to evaluating prognosis and stage migration effect even in a single institute and enable to identify those who need meticulous treatments and follow-up in patients with gastric cancer. Neuronal Nitric Oxide synthase (nNOS) is an attractive challenging target for the treatment of various neurodegenerative disorders. Dexmedetomidine, acting through central alpha-2 adrenoceptors, prevents opiate-induced muscle rigidity in the rat. The high variability of the number of cramps experienced suggests that clinical trials will need to use crossover designs or large numbers of participants, even when the treatment effect is substantial.

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A bifunctional fluorescent oligonucleotide probe for small molecules and protein detection has been developed based on turn on fluorescence response via the target induced structure-switching of molecular beacon. Data were collected from a sample of 106 African American community-dwelling adults in the metropolitan Washington, DC, area. A total of 204 Young people consecutively referred to a specialist public mental health service in Melbourne, Australia were approached and 150 consented to participate.

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Vasodilator drugs, particularly intravenously infused nitroprusside and an orally administered combination of hydralazine and isosorbide dinitrate, exert a profoundly favorable hemodynamic effect in the setting of heart failure complicating a prior myocardial infarction. At 68 years all completed the Geriatric Depression Scale and 867 completed the Geriatric Mental State Examination.

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In glaucoma, laser treatment represents a step between the medical treatment and surgery and is a very good alternative when the medication in inefficient or is not well tolerated. The patients who had palatine-tongue position in degree 1 to 2 (no significant tongue enlargement) were defined as stage I (32 cases). This chapter first describes the catalytic role of AfsA-like enzyme then provides details about methods for the discovery and characterization of potentially novel signaling molecules. Previous research has reported that the mean of depressive symptoms is stable in the general population through middle adulthood.

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Vinexin localizes at sites of cell-extracellular matrix adhesion in NIH3T3 fibroblasts and at sites of cell-cell contact in epithelial LLC-PK1 cells. A rat cDNA clone encoding the novel membrane protein of the neurotransmitter transporters family was cloned and sequenced. Out of 11 patients with abnormal liver, cytomegalovirus DNA sequences were shown in 5.

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Increased serum adiponectin levels in relapse compared to remission might be the reflection of a compensatory response to nephrotic state characterized by massive proteinuria, hypoalbuminemia and hyperlipidemia. Local parametric instability near elliptic points in vortex flows under shear deformation. D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics. A fundamental aspect of multicellular development is the patterning of distinct cell types in appropriate locations. Experimental evidence against diffusion control of Hg evasion from soils.

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Neuropsychological testing in a rural African school-age population: evaluating contributions to variability in test performance. PM-SNOM investigation of the chiroptical properties of single ribbon-like nanosized J-aggregates formed by acid induced aggregation of tris-(4-sulfonatophenyl)phenylporphyrin is reported. In recent years, increase attention has been directed towards the role of prostaglandin in macrophage function. Help is mostly required for walking: 58 percent of the disabled population need such a help. The underutilization of street markets as a source of food security indicators in famine early warning systems: a case study of Ethiopia.

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Rate of telomere shortening and metabolic and cardiovascular risk factors: a longitudinal study in the 1934-44 Helsinki Birth Cohort Study. Clinical observation of propofol combined with misoprostol for painless induced abortion Distribution of effects on PPT did not support either neural segmental or Traditional Chinese Medicine channel theories.

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On the other hand, photodynamic therapy has the curative potential for patients with early superficial lung cancer using low power laser. Skewed X-inactivation was observed here for the first time in carriers of PAK3 mutation.

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Management and prevention of post-transplant malignancies in kidney transplant recipients. Case-control study of the association between the use of cellular and cordless telephones and malignant brain tumors diagnosed during 2000-2003.

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Pharmacology of locus coeruleus spontaneous and sensory-evoked activity. At a time when health and social care services in European countries are under pressure to contain or cut costs, informal carers are relied upon as the main providers of long-term care. Transposon mutagenesis of this pathogen using the Himar1 system resulted in the isolation of an omp10 operon insertional mutant referred to as the omp10::himar1 mutant. Elderly patients with myocardial infarction complicated by cardiogenic shock are less likely to be treated with invasive therapies than younger patients with shock. Long-term outcome of revascularization with composite T-grafts: Is bilateral mammary grafting better than single mammary and radial artery grafting?

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Data from the Surveillance, Epidemiology, and End Results database for 18,294 patients who underwent hysterectomy and lymphadenectomy were analyzed. Capacity of the clinical picture to characterize low back pain relieved by facet joint anesthesia.

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One model fits all: Explaining many aspects of number comparison within a single coherent model-A random walk account. Macrozoom microscopy helps to screen for interesting muscle phenotypes, while confocal microscopy in multiple locations over 4-5 days produces time-lapse images that are used to quantify changes in cell morphology. Can analgesia be given safely to patients with suspected appendicitis prior to surgical evaluation without masking physical signs and symptoms? Noticeable differences in the results were detected for the 4 configurations.

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The technique is a combination of the well proven approach for percutaneous catheterization of the vein and a technique used in the implantation of permanent pacemaker leads. Synthesis of Amphiphilic Block Copolypept(o)ides by Bifunctional Initiators: Making PeptoMicelles Redox Sensitive. Increased mesohippocampal dopaminergic activity and improved depression-like behaviors in maternally separated rats following repeated fasting/refeeding cycles.

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The aim of the present study was to investigate the effects of comorbid obsessive-compulsive symptoms (OCS) on the perception of insincere speech (e.g., sarcasm and white lies) in patients with first-episode psychosis. Trajectories of Symptom Occurrence and Severity From Before Through Five Months After Lung Cancer Surgery. On examination he had bilateral polyphonic wheeze and evidence of distal asymmetric sensory neuropathy with motor weakness. SSeCKS (src suppressed C kinase substrate) was identified as a PKC substrate/PKC-binding protein, which plays a role in mitogenic regulatory activity and has a function in the control of cell signaling and cytoskeletal arrangement.

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It is therefore not surprising that white adipose tissue function can be perturbed by altering mitochondrial components or oxidative capacity. Neuropsychiatric symptoms during treatment with interleukin-2 and interferon-alpha. Peripheral and cardiac adaptive mechanisms in heart failure: the role of the renin-angiotensin system and its inhibition Template proformas produce a high rate of inclusion of data items in reports of colorectal carcinoma resection specimens.

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A clinically controlled trial demonstrated a significant treatment effect favouring modified CIMT using the Assisting Hand Assessment at two and six months. In contrast, no histological change was observed throughout these areas of the brains in the JHMV-infected mice after injection with pRSV-mRNA7. The occurrence of intestinal metaplasia on biopsy samples was determined on repeated endoscopies in 177 patients enrolled in a surveillance program for CLE. Interactions between mefloquine and the anti-fibrotic drug silymarin on Schistosoma mansoni infections in mice. The patient was released home on the 10(th) day following the operation.

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Heme oxygenase-1 induction in skeletal muscle cells: hemin and sodium nitroprusside are regulators in vitro. Moreover, the hyperglycaemia induced by 60 mg/kg streptozocin is greater in 8 week old rats than in 4 or 6 week old rats, suggesting an influence of age on streptozocin-induced hyperglycaemia.

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The synthesized graphene sheets are characterized using UV-vis spectra, Fourier transform infra-red (FT-IR) spectra, transmission electron microscope, X-ray photoelectron spectra (XPS) and Raman spectroscopic techniques. These data have important implications for further clarifying the macroenvironmental effect of cancer progression and provide new potential approaches for characterizing the tumor micro- and macroenvironment of breast cancer in both pre-clinical animal studies and clinical applications. Plasma HBV-DNA, HCV-RNA, and HIV-RNA were determined by PCR in 5 HBsAg/anti-HCV/anti-HIV positive patients, in 4 HBsAg/anti-HIV positive patients and in 82 anti-HCV/anti-HIV positive patients first observed at a Unit of Infectious Diseases in Naples (Italy) from 1990 to 2000 (follow up 6-16 years). Abdominal wall metastases seven years after resection for carcinoma of the appendix. This stimulation of epithelial transport is accompanied by systemic and local hemodynamic effects.

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Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate. It suppresses murine and leporine immune responses to antigens unrelated to the inducing virus. The data suggests that gadolinium-enhanced inner ear MR imaging is useful for diagnosis of delayed endolymphatic hydrops (DEH) because it is independent of inner ear function, and the size of the affected endolymphatic space is clearly enlarged. For the micromachined membrane concentrator concentration factors of 6-8 were achieved, at much lower flow rates than predicted by the model.

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Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well. To identify novel molecular targets controlling incretin secretion, we analyzed enteroendocrine cell pathways important for hormone biosynthesis and secretion. Much enhanced sensitivity is achieved by use of a large aqueous phase/solvent volume ratio. Quantitation of estrogen receptor content and Ki-67 staining in breast carcinoma by the microTICAS image analysis system. The secretion of aldosterone and its responses to stimulation have been studied in rat adrenal zona glomerulosa tissue incubated as intact capsules or as collagenase-dispersed cell suspensions, and in intact perfused rat adrenal glands.

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The unilateral lesion produced a significant decrease of self-stimulation using the electrode ipsilateral to the lesion, without any modification of the stimulation using the contralateral electrode. However, in patients with septic AKI, the deleterious consequences of overzealous fluid therapy are increasingly being recognized, while concerns exist both about the possible adverse effects of excessive and/or insufficient fluid removal with diuretics or ultrafiltration in CRS. A marked increase (up to 100 times with respect to saturated solution) of AgSD concentration in micelle dispersion was obtained. Following conjugate addition of water a reversible water elimination yielding cis-cinnamoyl derivatives accompanied by acyl migration products was observed in model systems.

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Because none of the chemicals tested increased the concentration of lolitrem B in the herbage, they are unlikely to be directly implicated in perennial ryegrass staggers in grazing animals. Facial Skin Lesions in Children Caused by Nontuberculous Mycobacteria. On the other hand, LPS-induced levels of the anti-inflammatory cytokine IL-10 were suppressed in pregnant mice. There was a depressed function of elements in the mononuclear phagocytic systems and inhibited reserve phagocytic abilities during adaptation to psychoemotional stress.

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This study describes the involvement and the histological alterations found in the parotid glands of 100 patients who died with AIDS. Synthesis of Several Naturally Occurring Polyhalogenated Monoterpenes of the Halomon Class(1). Open thoracoabdominal aortic aneurysm (TAAA) repair traditionally carries substantial perioperative morbidity and mortality, primarily from distal aortic ischemia.

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To describe the essence of the self-experience of adolescents with Tourette syndrome in the context of peer interaction. This recent method achieved a marked improvement in simulation speed and reduction in the number of time-steps required to complete a simulation run, compared with the exact algorithm, by sampling only the net diffusion events, instead of sampling all diffusion events. The actin cytoskeleton within the shoot cells is necessary for normal amyloplast displacement upon gravistimulation, which leads to the gravitropic bending. The introduction of 5-HT3 receptor antagonists has stimulated interest and research in this area. The autoxidation was continuously monitored by measuring the oxygen consumption of LME under UV light exposure and isobaric conditions, and, in parallel, by determining the carbonyl and peroxide values of LME.

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The eluted cholesteryl ester fraction was then analyzed by HPLC. A three-compartment (air- grass-milk) milk contamination model for 131I has been applied to atmospheric, grass and milk data, following the April 1986 nuclear accident at Chernobyl.

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A case of hepatic metastasis of gastric hepatoid adenocarcinoma mistaken for primary hepatocellular carcinoma Recently published reports suggest that the combination of aminoglycosides with ceftazidime may increase the risk of renal disease in cystic fibrosis. Further analysis, focused on EDS types III and IV cells, showed that partial matrix correction in EDS type III cells can be obtained by their cultivation over a feeder of EDS type IV fibroblasts, but not vice versa. In turn, the low availability of some metals controls the rate of photosynthesis in parts of the oceans and the transformation and uptake of major nutrients such as nitrogen. We included studies that assessed the use of smartphone interventions in the reduction of COPD exacerbations compared with usual care.