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The level of node involvement and recurrence rates were assessed in cN0 laryngeal and hypopharyngeal carcinoma patients in order to develop appropriate guidelines for the treatment of the neck. Microcolonies of the virulent strains had an elongated appearance and exhibited extensive cording. cerevisiae ero1-1 strain, both eroA and ervA were able to complement the temperature and DTT sensitive phenotype, although a truncated eroA, missing the putative HEEL ER-retention signal was unable to complement as well as the full-length eroA gene. The influences of different acid mixing ratios and of the etching solution density depending on the silicon content is considered and discussed in detail.

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Chemotherapy was tailored according to International Federation of Gynecology and Obstetrics risk scoring system. The occurrence of in vivo iron toxicity in the human body can be categorized into iron overload and non-iron overload conditions. Treatment outcome results from the Bulgarian Acromegaly Database: adjuvant dopamine agonist therapy is efficient in less than one fifth of non-irradiated patients. Protein malnutrition also reported to alter glutamate level and some of its metabolic enzymes. Inflatable penile prostheses were implanted in 19 patients who had undergone cystoprostatectomy with prophylactic urethrectomy.

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Furthermore, corallocin B showed antiproliferative activity against HUVEC and human cancer cell lines MCF-7 and KB-3-1. Discontinuation of anti-TNF therapy in patients with inflammatory bowel diseases (IBD) in remission remains a controversial issue. Thirty-one unpaired (1 fresh and 30 formalin fixed) adult cadaveric lower extremity specimens were dissected. Under general anesthesia the inferior alveolar nerves of 8 cats were transected unilaterally and the cut ends reapposed. We describe a protocol for in vivo postoperative imaging of cochlear implants by CBCT.

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Retrospective review of serum creatinine and creatinine-based measures of estimated glomerular filtration rate in an amputee population. outer root sheath cells, sweat ducts and eccrine sweat gland cells). In Section 5, we consider the scope of perceptual learning, contrasting recent research, focused on simple sensory discriminations, with earlier work that emphasized extraction of invariance from varied instances in more complex tasks.

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This study was conducted to assess protective effect of an antioxidant protein, sericin, on tumor promotion in the 7,12-dimethylbenz (alpha) anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol 13-acetate (TPA)-promoted mouse skin tumorigenesis model. Time-resolved fluorescence and anisotropy studies showed that oxidized gramicidin in methanol had shorter fluorescence lifetimes and a shorter rotational correlation time compared to non-irradiated gramicidin. The atrocities of Nazi doctors as revealed by the Nuremberg trial caused the World Medical Association in 1948 to formulate a modernized version of the Hippocratic Oath.

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Cells with the highest RNA levels correspond to those with the highest plating efficiency, and those with intermediate RNA levels are those with the lowest plating efficiency. The authors performed a pilot randomized controlled trial of total-body screening to assess the feasibility of a full-scale study. To investigate the relationship between clinical and demographic characteristics and mortality in patients with organophosphate poisoning. A controlled evaluation of paraspinal EMG biofeedback in the treatment of chronic low back pain. The expression pattern of the GFP reporter system was compared with that of the LacZ reporter system.

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We undertook the endoscopic examination of the middle meatuses in 250 patients. A variety of neoplasms involve both the infratemporal fossa and the base of the middle cranial fossa, in medial proximity to the cavernous sinus and orbital apex. Odor-induced persistent discharge of mitral cells in the mouse olfactory bulb. Thus, it appears that some degree of structural homology exists between the rat and human benzodiazepine receptors. The short form L-myc proteins are present in the cytoplasmic fraction, though diffusion of the short forms from the nucleus during cell fractionation cannot be ruled out.

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Cryopreservation of pancreatic islets prior to transplantation: a comparison between UW solution and RPMI culture medium. Tissue engineering is the new science that has come to make possible the growth of new organ tissue from small fragments of healthy tissue, thus partially or totally restoring the lost functions of ill tissues or organs, as shown by the achievements made with the culture of skin, cornea or cartilage. Multiple studies have investigated the prognostic role of red blood cell distribution width (RDW) for patients with heart failure (HF), but the results have been inconsistent. The noise exposure results obtained did not indicate that there was a significant increase in the risk to potential noise injury from PSP use alone.

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Matrix metalloproteinase-9 and vascular endothelial growth factor expression change in experimental retinal neovascularization. In three patients chest discomfort occurred during planned 1-hour infusions of liposomal amphotericin B (AmBisome) 3 mg/kg/day during an open-label trial. Several surgical approaches have been proposed with more and more aggressivity. All measures analysed had elements of a holistic approach so far that they were not wholly biological.

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Multiple logistic regression was used to develop a parsimonious prognostic model. The system has a thin circular piece with at least two holes for subcutaneous fixation, one or several conducts for lumina and a hollow cylindrical part in one side, screwed exteriorly and flat inside, with an oriented protuberance. Secondly, clustering with dendritic cells appears to be essential for mitogenesis.

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The meeting with the family of a hospitalized patient dying with advanced cancer or hematologic disease in which the limitation of life-sustaining interventions is discussed can be a challenge, particularly for junior physicians. The aim of this study was to develop a suite of KPIs for prehospital emergency care in Ireland. Responsiveness to acute psychostimulant administration varies across ontogeny. The IC administration of U50,488 promoted a threefold increase in motor activity, which was predominated by movements of caudal regions of the body (rearlimbs, body trunk, and tail).

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New development of laparoscopic ultrasound and laparoscopic pelvic lymphadenectomy in the management of patients with cervical carcinoma. Secondly, the choice of the grid size is shown to depend largely on the spatial patterns.

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Even though they are included in the classification of nonsmall cell carcinomas, they have a biological behaviour and physiological response to treatment more like small cell carcinomas of lung. CONSIDERATIONS ON THE SYNDROME OF SHEEHAN (DESCRIPTION OF A CASE) Molecular and biological interaction between major histocompatibility complex class I antigens and luteinizing hormone receptors or beta-adrenergic receptors triggers cellular response in mice.

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Very small air bubbles (10 - 70 microl) cause clinically significant variability in syringe pump fluid delivery. These image schemata are schematic structures that are continually requested by individuals in their perception, bodily movement and interaction with surrounding objects. Within the past decade, toxic Pfiesteria outbreaks have been documented in poorly flushed, eutrophic areas of the largest and second largest estuaries on the U.S.

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This study aimed to evaluate the relationship between perceptual assessment and acoustic measurements of nasality using controlled speech stimuli. This highly reactive species is thought to contribute to bacterial killing by interaction with diverse targets and nitration of protein tyrosines. National comparisons of clinical outcomes for thoracic surgical procedures should be interpreted with caution when using partial databases.

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Upon its completion, many Dutch EPs feel that they lack some of the skills and the knowledge necessary to be fully prepared for the challenges of emergency medicine. Thus, these novel findings indicate that PSGL-1 may be a useful target to protect against sepsis-induced accumulation of neutrophils and tissue damage in the lung. We describe a sensitive and specific liquid-chromatographic assay for pentoxifylline and three of its metabolites in human plasma and urine.

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Our findings indicate that in both intercity and within-city settings the proposed algorithms more effectively capture the spatial locations where people reside than traditional commonly-used network metrics. The incidence of HAIs is higher than in other developed countries. Adenosine Receptor Stimulation by Polydeoxyribonucleotide Improves Tissue Repair and Symptomology in Experimental Colitis. Beneficial effects on the retina likely are mediated by both direct and indirect mechanisms.

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Investigation of a macrobending micro-plastic optical fiber for refractive index sensing. Accordingly, we observed no preferential binding of Hap46 to overlapping DNA fragments covering the sequence of the cytomegalovirus (CMV) early promoter, thus suggesting non-specific binding. We combined multiple approaches to assess the extent to which fitness of a widespread native annual legume, Chamaecrista fasciculata, decreases at and beyond its northern and western range edges, and how this is influenced by the presence of neighbors. These data indicate a remarkable double dissociation of fear-like and anxiety-like behaviors involving netrin-G1 in excitatory and inhibitory neurons, respectively.

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Arsenic trioxide induces apoptosis of rat hepatocellular carcinoma cells in vivo. All organs were of normal appearance, and histological examination of tissues, blood biochemistry and haematology results showed no abnormal changes. This semiconductor laser can remain single-mode, even at high pump power levels, while allowing tunability over a wide spectral range. Three-dimensional conformal radiation therapy and intensity-modulated radiation therapy combined with transcatheter arterial chemoembolization for locally advanced hepatocellular carcinoma: an irradiation dose escalation study. The performance of the subjects in trials with and without spike wave discharges was compared.

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The release of indomethacin from the prepared implants followed predominantly matrix diffusion kinetics. Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum. Symptomatic uncomplicated gall bladder stones may be treated by laparoscopic or open cholecystectomy or by non-surgical methods. In addition, DSS treatment significantly increased sucrose consumption in chronic unpredictable stress- (CUS-) treated mice.

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This data supports the notion that leucocyte myeloperoxidase may act to suppress the antiprotease screen afforded by alpha-1-PI by generating hypochlorous acid in the presence of chloride and respiratory burst-derived hydrogen peroxide, and in the microenvironment of lowered pH associated with degranulation. Separation of forward input description and feedback generated hypothesis, while using the difference in both descriptions at each of the modular units to control the refinement, enables robust recognition and has the potential for autonomous learning. Most of these proteins are encoded by multigene families, and most members within each family share significant similarities in structural features, but often exhibit differing expression profiles and physiological functions. However, pressures such as time, cost and the introduction of the Human Tissue Act have generated suggestions that there is a discrepancy between the published guidelines and what can realistically be achieved in daily practice.

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In recent studies, orally administered angiotensin II type 1 receptor blockers and angiotensin-converting enzyme inhibitors lower intra-ocular pressure (IOP), likewise topical application of these compounds, the effect being more prominent in ocular hypertensive eyes. Heterosteroids remain interesting due to their potential biological activities. In the other groups, no association between duration of illness and intensity of perceived dizziness could be seen. In half of these cases application of integrated care was reported.

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Trauma, instabilities and tumors of the cervical spine are treated with established methods of surgery. This cell-free system will be useful for the analysis of the function of replication enzymes and proteins as well as the characterization of ts mutants.

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Biological effectiveness of fast neutrons on a murine osteosarcoma. For investigating specific problems the data collected in the Swedish Urinary Bladder Cancer Registry have to be validated. Pumice Characteristics and Their Utilization on the Synthesis of Mesoporous Minerals and on the Removal of Heavy Metals. Vervets are known to raid crops, homes and gardens in suburban areas leading to human-vervet conflict.

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The aim of the study was to evaluate how patients assess their forearm and hand function after radial artery harvest for coronary artery bypass grafting (CABG). This study aims to assess the efficacy of 4 distant metastasis staging modalities, namely (1) conventional work-up comprising chest X-ray, liver ultrasound, and skeletal scintigraphy, (2) CT of the thorax, abdomen, and skeletal scintigraphy, (3) (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET), and (4) integrated FDG-PET/CT. Qualitative suggestions include refinement of OPIS components, enabling personalization of OPIS functionalities and proactive endorsements of OPIS by professionals. These, however, are not suitable for images containing text and artificial graphics. Feline cutaneous neuroendocrine carcinoma (Merkel cell tumour): clinical and pathological findings.

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The aim of the present study was to establish and validate HRM analysis for detection of promoter methylation on archival formalin-fixed paraffin-embedded tissues from colorectal cancer patients. We report about clinical experiences with the cardioplegia according to Bretschneider combined with deep selective hypothermia of the heart in 44 patients. Direct measurement of the initial and early ratios of proton extrusion to oxygen uptake accompanying cytochrome c oxidation by rat liver mitoplasts. Phosphoinositide and inositol metabolism was compared in glioma (C6), neuroblastoma (N1E-115) and neuroblastoma X glioma hybrid (NG 108-15) cells. The lamellar bilayer changes into a 3D cubic network in a small simulation box, attributed to the influence of neighboring images.

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For the purpose of increasing the PE in vitro, LA795 Vv-Vt tumor line was purified through culturing the cells as a clonogenic spheroid. Thyroglossal tract remnants are thought to be present in seven percent of the adult population. Do morphines improve the quality of analgesia with local anesthetics?

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Therefore, H2O2-resistant peroxidase and laccase should be exploited. Central trigeminocardiac reflex in pediatric neurosurgery: a case report and review of the literature. Successful treatment programs should include antifungal drugs and manipulations that correct the immunologic abnormalities that predispose the patient to Candida infections.

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These approaches are based on the sensitive assay of molecular markers in stool, blood, and urine samples. Inhibiting noradrenergic overactivity can be obtained by inhibiting thromboxane and concomitantly activating opiate receptors. The increase in mean arterial pressure (MAP) at each bolus dose of the first dose-response curve was found not to be significantly different from the corresponding value of the second dose-response curve in the four models of rat studied (i.e. Definitive management of acute cholecystitis or symptomatic cholelithiasis in exceedingly high-risk patients remains a clinical dilemma. Inadvertent spinal anesthesia during continuous epidural anesthesia in an infant.

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Methane producer status has a role in determining whether patient experiences diarrhea or constipation during 5-fluorouracil therapy. Corticotropin positively regulates its own receptors and cAMP response in cultured bovine adrenal cells.

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Local field irradiation in the regions of neck or axilla may be safely performed even without uterus shielding. For optimal therapy management an interdisciplinary consultation is necessary.

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Emerging evidence suggests that inflammatory cytokines are involved in pathophysiology of epilepsy. In addition, nonsensitized and sensitized groups showed distinct activity patterns, with heat-sensitization inducing increased phase coherence at the theta and beta ranges. The western corn rootworm, Diabrotica virgifera virgifera LeConte, is a major agricultural pest that is managed with transgenic corn, Zea mays L., expressing genes from Bacillus thuringiensis Berliner (Bt). They completed a functional magnetic resonance imaging (fMRI) task that required remembering names associated with pictures of famous faces.

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Mitochondrial biogenesis occurs in response to increased cellular ATP demand. Steps in the negative-differential-conductivity regime of a superconductor.

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Drosophila SAF-B links the nuclear matrix, chromosomes, and transcriptional activity. Furthermore, sera of northern elephant seals (Mirounga angustirostris) were tested to evaluate whether the harbour/grey seal ELISA is suitable for this seal species as well.

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Isolated Cortical Venous Thrombosis as a Mimic for Cortical Subarachnoid Hemorrhage. Two logistic regression analyses were conducted in anti-HCV-positive patients, including the entire sample and then on a subsample excluding sites with routine HCV RNA testing policies, using data stored in the VA Southern California Network data warehouse. Morphological peculiarities of female, host specific, geographical distribution of this poorly studied copepod species are briefly discussed. Ten matched patients with AD, who did not move, served as a control group. The volume of minor procedures performed by general surgeons increased slightly, with gains in vascular and endoscopic surgery.

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Nutrition and diet for healthy lifestyles in Europe: science and policy implications. The microwave launcher had the standard rectangular waveguide WR340 geometry.

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The tumor response and progression-free survival were evaluated. Mastoid cavity obliteration was performed with hydroxyapatite bone cement. The software development process is a complex process, especially when the software has to be released in a phased manner. In the adult rat brain, the catalytic subunits alpha1 and alpha2 are present in neurons throughout the brain.

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Computer-Detected Attention Affects Foreign Language Listening but Not Reading Performance. In particular, the potential application of hemozoin crystals as an adjuvant may provide insights into the molecular mechanisms involved in immune responses to malarial infection and provide a rationale for the design of vaccines against malaria as well as other immunological disorders such as allergies. Progress in application of Bayley scales of infant and toddler development third edition This review (1) discusses the biologic inter-relationship between prostate cancer, ADT and MetS, (2) evaluates the current literature in support of exercise in targeting MetS and (3) describes the physiological mechanisms by which exercise may favorably alter MetS risk factors in prostate cancer patients on ADT.