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Kofron (Clarithromycin)

Kofron is a semisynthetic macrolide antibiotic, structurally very similar to erythromycin. It inhibits protein synthesis by penetrating the cell wall and binding to the 50S ribosomal subunit. The absolute bioavailability of Kofron after oral administration is 50-55%, which probably underestimates its systemic activity, as it undergoes extensive first pass metabolism to its active metabolite, 14-hydroxyKofron. Limited data are available on the distribution of Kofron in humans. It appears to be distributed into most body tissues and fluids. However, no data is available on CSF penetration of Kofron. Elimination of Kofron follows nonlinear kinetics. It is extensively metabolized in the liver and excreted as parent drug and metabolites in urine, and faeces.

Other names for this medication:
Clarithromycin, Biaxin, Abbotic, Aeroxina, Biclar, Binoclar, Bremon, Clabel, Clamycin, Clarimac, Clarimax, Clarimed, Clarimycin, Claripen, Claritt, Clariva, Clariwin, Clarix, Claromycin, Claron, Cleron, Emimycin, Euromicina, Finasept, Fromilid, Infex, Kailasa, Kalixocin, Klabax, Klabet, Klabion, Klarimac, Klarimax, Klarithran, Klax, Klaz, Klerimed, Kofron, Krobicin, Lekoklar, Macladin, Maclar, Macrobid, Macrol, Monozeclar, Naxy, Synclar, Taclar, Veclam, Vikrol, Xylar, Zeclar, Zeclaren,

Similar Products:
Valtrex, Bexon, Fasarax, Antiplar, Antiox, Sereupin, Zoloder, Esomeprazol, Meprazol, Stromectol, Tenofovir, Zival, Benestan, Binoclar, Ketoconazole, Supraviran, Pradif, Venlafaxine, Zargus, Rozex, Esoprazol, Chear, Eslorex, Julmentin, Warfarin, Omizac, Esomezol, Acyl, Levocine, Remoxy, Levoflox, Helicid, Neurotin, Novacan, Teranex, Cefakind, Moxatag,

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Cyclo-lib: a database of computational molecular dynamics simulations of cyclodextrins. A navigation-guided, endoscope-assisted retrosigmoid inframeatal approach was performed on 6 cadaveric heads in the semisitting position, displaying an area from the internal acoustic meatus to the lower cranial nerves and exposing the intrapetrous internal carotid artery. A new quantitative DNA-methylation analysis of MSI colorectal cancers helps to separate sporadic colorectal cancers from HNPCC-candidates Multidimensional Diagnostic Criteria for Chronic Pain: Introduction to the ACTTION-American Pain Society Pain Taxonomy (AAPT). PSM-mec is a secreted virulence factor that belongs to the phenol-soluble modulin (PSM) family of amphipathic, alpha-helical peptide toxins produced by Staphylococcus species.

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No correlation was found between colostrum and urine sodium and potassium levels, and colostrum and serum potassium levels, however, there was a correlation found between colostrum and serum sodium levels (r: 0.311, p less than 0.05). The current Sectorial Program on Health 2013-2018 represents a window of opportunity to position research findings that promote health equity policies. The clinical data of 66 patients with rectal cancer from March 2011 to March 2013 were prospectively analyzed.

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Anesthesia without muscle relaxants has been reported to be effective for early extubation after thymectomy, but postoperative respiratory status of the patients has not been studied intensively. For other chronic disease states there have been clinical studies supporting its use, but they have not yet been approved as a indications by the FDA. SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan. In vertebrates, the mechanisms underlying behavioral selection are poorly understood. In the present study, we investigated MMP-2 and MMP-9 in oral fluids of healthy subjects and periodontitis patients and the contributions of different oral cells to the enzyme production.

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Symptomatic and quality of life outcomes after site-specific fascial reattachment for pelvic organ prolapse repair. The study also heralds an important step towards indicated prevention of persistent depression, which may reduce the burden, stigmatization, disability and economic consequences of this disorder.

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A new graphic method for differentiating mononuclear and polynuclear complexes and for determining their stability constants. Is an excessive number of prenatal echographies a risk for fetal growth?

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Cat scratch disease (CSD) commonly occurs secondary to Bartonella henselae infection, and the diagnosis has traditionally been made by microscopic findings, the identification of organisms by cytochemistry, and clinical history. CD44 is of functional importance for colorectal cancer stem cells. Peripheral blood leukocytes obtained from BSA-sensitized H line chickens exhibited lower proliferative responses to concanavalin A than peripheral blood leukocytes from C and L line chickens.

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The primary focus of this study is to identify the correlation between fluctuating level of attention and its implications on the cardiac rhythm recorded in the ECG. The percentage of rats with diarrhea decreased and a stronger protection was afforded by the repeated treatment. Finally we got the death percentage from stroke in relation to overall mortality.

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Using human gastric epithelial cells in culture and broth culture filtrate from a VacA-producing H. Volumes of the major organelles within zona fasciculata steroidogenic cells. We assessed apoptosis and necrosis by annexin V-propidium iodide (PI) labeling, and caspase-3 activity by fluorescence assay.

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In vitro and in vivo antibacterial activities of T-3262, a new fluoroquinolone. The LAC has the potential to be used as a metric of development of tissue-engineered cartilage.

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Inappropriate prescribing (IP) in older patients is highly prevalent and is associated with an increased risk of adverse drug events (ADEs), morbidity, mortality and healthcare utilisation. Multiple regression models were used to analyze the association between blood pressure and vitamin C and fruit and vegetable intakes. The binding activity and surface accessibility of the solute binding protein of PiuA were studied. Studies examining sleep and psychopathology should control for psychological co-morbidity. To evaluate the associations between serum complement factor 3 (C3) and several anthropometrical, biochemical and lifestyle features in healthy young adults, emphasizing on the putative effect of selenium intake on C3 concentrations.

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Mouse cytochrome b561: cDNA cloning and expression in rat brain, mouse embryos, and human glioma cell lines. Use of celecoxib correlates with increased relative risk of acute pancreatitis: a case-control study in Taiwan.

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Hygienic establishment of the maximum permissible concentration of the calcium salt of dimethyldithiocarbamic acid in the soil When a small amount of water was added as the internal aqueous phase in the W/O/W-multiple-emulsion method, the encapsulation efficiency was found nearly triple of that for the O/W-emulsion method.

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Parent artery occlusion by endovascular coiling is the treatment option for these cases. The antinociceptive and anti-edematogenic effects of peripheral benzodiazepine receptor (PBR) ligands, Ro5-4864 (7-chloro-5- (4-chlorophenyl)-1,3-dihydro-1-methyl-2-H-1,4-benzodiazepine-2) and PK11195 (1-(2-chlorophenyl)-N-methyl-N(1-methylpropyl)-3-isoquinoline carboxamide), were studied in an experimental model of carrageenan/LPS -induced arthritis in rats. In particular, cetuximab in combination with curative-intent radiotherapy in head and neck cancer increases median survival over radiation alone. Polytherapy is associated with younger kids and being treated in a university hospital. Clarithromycin was the most active drug tested, followed by the other macrolides, tetracycline, and ciprofloxacin.

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To determine intraoperative complications of cataract surgery over the period 2006 to 2010. After a week, the strips were removed, and the number of bacteria on the strips and in the surrounding tissue were determined. COAGULATION, FIBRINOLYTIC ACTIVITY AND VISCOSITY OF THE BLOOD IN PATIENTS WITH CEREBRAL CRISIS Each patient presented with signs and symptoms suggestive of a localized disease process: ischemic limb, mediastinal mass, dementia, and pneumonia.

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Weekly topotecan for recurrent small cell lung cancer - a retrospective Anatolian Medical Oncology Group study. To estimate the cost effect of implementing generics, the most favorable equivalent generic was assigned to each anti-dementia drug. The current concepts of the role of eicosanoids in the pathogenesis of respiratory organ diseases Antiglucocorticoids that act as antagonists at the glucocorticoid receptor (GR) level may be used to block or modulate the undesirable effects of glucocorticoid excess (from endogenous or exogenous origin).

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Connexin43 gene defect is obviously associated with abnormal heart morphogenesis. Intake of omega-3 and omega-6 fatty acids and risk of ovarian cancer. Identification and characterization of kinetically competent carbinolamine and alpha-iminoglutarate complexes in the glutamate dehydrogenase-catalyzed oxidation of L-glutamate using a multiwavelength transient state approach. A fixed dose of minocycline (50 mg/kg) combined with three different doses of ceftriaxone administered for 7 consecutive days yielded a potentiating effect in the enhancing latency time to noxious thermal stimulus remaining until the 14th day post-surgery.

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Stimulation of CD3/T cell receptor, CD2 or CD28, as well as activation with phorbol esters, can induce within minutes an increase in beta1 integrin-mediated adhesion of T cells to fibronectin. The prophylactic use of monoclonal antibodies in renal transplantation. The medium term outcome of the Omnifit constrained acetabular cup. The high concentration of the radioactivity in the argon carrier gas makes it possible to record a scintigram after a single deep breath. To investigate how some organisms might be able to developmentally compensate for increasing turbidity, we reared guppies (Poecilia reticulata) in either clear or turbid water.

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Twenty-two year follow-up of an Indian family with dysferlinopathy-clinical, immunocytochemical, western blotting and genetic features. Exposure to this agent led to a reduction in the degree of incorporation of carbon-14-lysine into the mucopeptide of the cell wall material and to an accumulation of N-acetyl glucosamine in the cell. For the other species, there are fewer data, making it difficult to draw conclusions.

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Rotational movement of the anterior maxillary segment by hybrid distractor in patients with cleft lip and palate. Virulence of a virE2 mutant was restored by mixed infection with strains carrying an intact vir region, but not with virA, virB, virD, virE, or virG mutants or chvA, chvB, or exoC mutants.

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Colorectal cancers, whether sporadic or hereditary, are caused by a defined set of molecular events. This prospective study suggests that progressively greater disturbances of vaginal flora, increase HIV acquisition during pregnancy and postnatally. Efficiency of signalling through cytokine receptors depends critically on receptor orientation. This study was designed to assess the validity of self-reported hysterectomy and oophorectomy. These results suggest that the conformations, fluidity, and elasticity of the tBLMs can be tuned and manipulated to conform to various requirements in theoretical investigations and technological applications.

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An Approximate Confidence Interval for Maximum Coefficient Alpha. Blood transfusion related paediatric HIV/AIDS in Ile-Ife, Nigeria. Vitamin E-bonded hemodialyzer improves atherosclerosis associated with a rheological improvement of circulating red blood cells. The modified field expressions involve the sums and differences of the Rayleigh-Sommerfeld diffraction integrals as descriptors of a bidirectional flow of energy in the near zones on either side of the aperture. Introspective attentional control (compared to exteroceptive attentional control) activated a common pregenual anterior cingulate (pACC) region in depressed and control subjects.

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To evaluate the ability of a group of scoliosis surgeons, not involved in the development of a new classification system, to accurately choose the corresponding curve classification of adolescent idiopathic scoliosis (AIS) cases and to evaluate the variability in the selection of operative approaches and both proximal and distal fusion levels in accordance with the new classification system in operative adolescent idiopathic scoliosis. We evaluated whether urinary excretion of tubular injury markers could be useful for early detection of gentamicin (GM)-induced renal damage in neonates. Plasma BDNF is a potentially useful clinical marker of endometriosis that is superior to NGF, NT4/5, CA-125, and CRP. While the pathogenesis is unclear, studies have demonstrated that the gastrointestinal tracts of patients with IBD are populated with increased levels of adherent and pathogenic bacteria. By applying a high frequency (of the order of megahertz) and high intensity (greater than or equal to a few megavolts per metre) electric field using the 3D nanoelectrodes, the generated dielectrophoresis attracted and then immobilized target biomolecules onto the tops of 3D nanoelectrodes, as a demonstration of active immobilization of biomolecules.

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