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Although the mechanical properties of bones are directly related to the determination of fracture risk, bisphosphonate effects on the related variables have scarcely been investigated. We interviewed surrogate decision makers for patients aged 50 and over, using a structured questionnaire that included a four-question CPR knowledge assessment similar to those used in previous studies.

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Ten patients who had undergone total pancreatoduodenectomy reconstruction using Billroth II type procedures (group PX) and 12 normal subjects (group C) were also enrolled in this study. Alkyl monolayer passivated metal-semiconductor diodes: 2: Comparison with native silicon oxide. THE PATHOGENIC ROLE OF FIBRIN DEPOSITION IN THE GLOMERULAR LESIONS OF TOXEMIA OF PREGNANCY. Ototoxicity of vancomycin: an experimental study in guinea pigs. Recently, however, exercise intolerance has been associated with specific defects in protein-coding genes of mitochondrial DNA (mtDNA), including mutations in genes for complex I, complex III, and complex IV.

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Tonography was performed at the start of the test, 1 1/2 hours later, and at its termination. 24 patients suffering from this disease were diagnosed and treated in Peking Union Medical College Hospital from 1978 to 2002.

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These tumor lines were all well or moderately differentiated adenocarcinomas, showing various velocities of growth, unrelated to the grade of histological differentiation. To investigate control mechanisms for ocular blood flow changes after dynamic exercise using two different methods. The clinical symptoms may not be relieved when the patients with SO dysfunction accepted cholecystojejunostomy. Recent studies have shown a broad prevalence of vitamin D deficiency in adults. Before starting the experimental diets, rats were orally treated with high doses of vitamin D for 4 d to accelerate atherogenesis.

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The length and methylation status of CGG repeats within the testes of a fetus carrying a full FXS mutation and another fetus carrying mosaicism FXS mutation were analyzed with Southern blotting and AmplideX FMR1 PCR. The current situation of mycobacterial chemoresistance and its implications for antitubercular treatment A short N-proximal region in the large envelope protein harbors a determinant that contributes to the species specificity of human hepatitis B virus. An increased concentration of TSH in the serum during surgery was followed by a significant post-operative decrease, possibly due to a suppressive effect of endogenous cortisol.

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The economic integration of the European Community (EC) targeted for 1992 has the potential to change the course of the development of the optometric profession in Europe. Transport of sodium into apical membrane vesicles prepared from fetal sheep alveolar type II cells. A novel method for determination of Hg, Se, Bi, As and Sb based on microwave digestion followed by continuous flow vapour generation atomic fluorescence spectrometry was developed.

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A fully 3D biomaterial containing overlapping gradations of structural, compositional, and biomolecular cues as seen in native orthopedic interfaces is described for the first time. To summarize evidence about the benefits and harms of psychological and pharmacologic therapies for adults with binge-eating disorder. Given the added costs of the US delivery device, prospective randomized data are needed to justify its widespread use for DVT treatment. Patient-rated outcome was assessed by completion of the Disability of Arm Shoulder Hand questionnaire (DASH).

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In adolescents and young adults, the TT-TG distance was statistically larger in knees with noncontact ACL tears than in intact-ACL control knees. In recent years metal-enhanced fluorescence (MEF) using silver particles has been reported for a number of fluorophores emitting at visible wavelengths.

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Our data show that the PAF effects were not mediated by TxA2, since administration of dazmegrel, a thromboxane synthetase inhibitor, did not ameliorate the acute renal failure caused by CsA. Previous gastrectomy may present technical difficulties for the endoscopist, but the problem appears to be decreasing. Our results suggest that gene expansion/contraction and positive selection are diversifying the mechanisms of pathogenicity across this species complex. The extract dosed at 60 mg/kg significantly increased LH and T following acute and subchronic administration and increased 3,4-dihydroxyphenylacetic acid levels in the nucleus accumbens, 30 min after the acute administration. In the early 1920s race biology was seen to constitute a legitimate science.

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Scientific knowledge is continuously increasing and recent studies should be considered and discussed to improve the results of daily emergency care. EVALUATION OF THE FUNCTIONAL ANATOMY OF THE THORACIC DUCT BY LYMPHANGIOGRAPHY. Due to the age-associated nature of most of these disorders and the demographic transition towards an overall older population, efficient therapeutic intervention strategies will need to be developed in the near future. Use of complementary and alternative medicine in patients with health complaints attributed to former dental amalgam fillings.

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Polymorphism, localization and geographical transfer of mitochondrial DNA in Mus musculus domesticus (Irish house mice). Surgery improved quality of life, even in cases of surgical failure or recurrent disease. Phase II study of the farnesyltransferase inhibitor lonafarnib with paclitaxel in patients with taxane-refractory/resistant nonsmall cell lung carcinoma.

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In the current study, sentences were segregated from multi-talker babble and from cafeteria noise using an algorithm that employs deep neural networks to estimate the ideal ratio mask. The analysis also allowed identification of transcripts predicted to be differentially expressed in brain tumor stem cells. These results suggest that complete and early virus replication control as a result of early HAART leads to a marked reduction of T-cell oligoclonality and is an essential prerequisite to the development of a polyclonal immune response in HIV-1 infected infants. Those episodes coded as such, according to the ICD-9-CM, in the discharge reports of all the patients hospitalized during 2005-07 in the entire Spanish territory, were selected.

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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that results in the selective loss of motor neurones. Despite increased focus on improving palliative care in the emergency department (ED), there is little research on how to best address the specific needs of this patient population. Further research is needed to identify effective strategies to reduce stress and decrease coffee and energy drink intake to minimize their negative effect on sleep quality and academic performance in podiatric medical students.

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The access to the nerve should be as atraumatic as possible and no muscular tissue should be incised or transected in order to lower postoperative morbidity and enhance the welfare of the animals. The multiple regression analysis revealed that the right-sided tumor localization and overexpression of MET were associated with shorter overall survival.

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In vivo, alterations of the anti-ribosome binding site region in the loop of FinP stem-loop I reduced the ability of the mutant FinP to mediate fertility inhibition and to inhibit TraJ expression when expressed in trans at an elevated copy number. Kinetoplast DNA minicircles: high-copy-number mitochondrial plasmids. If human platelets react to uric acid in the same manner as rat platelets this might explain the link that has been suggested between hyperuricaemia and ischaemic heart disease. Enlargement of air spaces with fibrosis in the anterior portions of both lungs is suspected to be due to tissue necrosis and high mechanical ventilatory pressures.

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As such, the results of this study can greatly modify the cognitive rehabilitation strategies. In the rat, immunopositive fibres in the circular muscle were most abundant in the ileum, whereas in the guinea-pig it was the colon circular muscle that was most richly innervated.

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Post-ultraviolet DNA synthesis kinetics were investigated in the Escherichia coli uvrA recA strain and its isogenic counterpart, overproducing single-strand DNA-binding protein (SSB). HISTOLOGICAL AND ENZYMATIC CHANGES IN THE LIVERS OF RATS FED THE HEPATIC CARCINOGEN DIETHYLNITROSAMINE.

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It is hypothesized that natural selection has favoured the production of meiospores in larval female mosquitoes rather than congenital transfer of infection to progeny via ovarian infection as a strategy for achieving greater transmission success. An algorithm is described here for the construction of a map of hydrogen-bonding regions at protein surfaces directly from the Brookhaven Protein Data Bank coordinates. Intralesional steroid injection to prevent stricture after endoscopic submucosal dissection for esophageal cancer: a controlled prospective study. Synaptic regulation of action potential timing in neostriatal cholinergic interneurons.

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We propose an original diffraction grating demultiplexer device with a very small footprint, designed for the silicon-on-insulator waveguide platform. Appropriate use of work restriction and erythromycin prophylaxis may decrease the likelihood of institutional outbreaks. Women with HIV infection are at high risk of harbouring HPV and of developing lower genital tract neoplasia. Can we improve the management of acute coronary syndromes in primary care? The patient, who went through the menopause 12 years previously, had presented with a painful perineal mass for 1 year, which was subsequently diagnosed as a postmenopausal perineal leiomyoma.

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Programs targeted to anomie, loss of traditional male roles, and violence and alcoholism are among the most urgently needed. If not functioning, the peroneal nerve is often severely stretched, and no treatment to date has been very encouraging. Interviews with 13 young adults with type 1 diabetes and 13 parents 2 years after transfer to adult diabetes care were conducted during 2006-2007. This regulatory change will have broad operational implications for practitioners serving the health care needs of long-term care residents.

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This latter result in intact pregnant animals contrasts with previously reported decreases in glucuronyltransferase activity in isolated liver preparations from pregnant rats. Structural analysis of isoform-specific inhibitors targeting the tetrahydrobiopterin binding site of human nitric oxide synthases. Our study provides growing support for a potential link between heavy metal homeostasis and host switching and reveals potential targets for rational design of new intervention strategies against malaria. The efficiency of 4 could be attributed to its high acidity, conferred by the sulfonyl moiety.

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LMP1 is an integral membrane protein containing six transmembrane segments and a cytoplasmic domain at the C terminus that binds to intracellular TNFR-associated factors (TRAFs). OASIS mRNA expression was observed in the inner enamel epithelium during the cap and bell stages (E14.5-E18.5) in the preodontoblasts during differentiation stage (E18.5-P0) and in the differentiating odontoblasts during the early secretory stage (P2.5-P4.5). Tail flick latency, an index of hyperalgesia, was assessed using analgesiometer.

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Tumors of several organs have been shown to bear cell surface receptors for insulin-like growth factor I (IGF-I), and to exhibit dependence on this mitogen for optimum proliferation both in vivo and in vitro. Molecular mechanisms of altered cholesterol metabolism in rats with spontaneous focal glomerulosclerosis. The transport rate increased when ethanol as an electron donor was added, so the transporter was an energy-dependent active one. In situ 13CO2 pulse labelling of field-grown eucalypt trees revealed the effects of potassium nutrition and throughfall exclusion on phloem transport of photosynthetic carbon. This review summarizes the occurrence of eremophilane-type sesquiterpenes and research progresses on their biological activities since the 1990 s.

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Proper neuron to glia interaction is critical to physiological function of the central nervous system (CNS). Korean version of the caregiver quality of life index-cancer (CQOLC-K).

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External biliary fistulas associated both with open and laparoscopic biliary surgery, need a quick solution to prevent local and general complications. Selenalysine is more effective than lysine both on glyceraldehyde 3-P transformation into methylglyoxal and on subsequent methylglyoxal polymerization. Follow-up studies of neuroleptic-treated groups with varying proportions of patients showing TD, by contrast, tend to show increased TD because new TD cases more than offset improvement. Twice-daily administration of xenin-25(gln) in high fat fed mice did not affect food intake, body weight or circulating insulin concentrations but significantly decreased blood glucose from day 9 onwards.

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Relief of postoperative right ventricular outflow tract (RVOT) obstruction with transcatheter pulmonary valve replacement (TPVR) results in functional improvement in the short term which we investigated at baseline (BL), early follow-up (FU), and midterm FU after TPVR. Previous studies of the conformations of peptides spanning the length of the alpha-spectrin SH3 domain suggested that SH3 domains lack independently folding substructures. Pre-operative embolization for spontaneous rupture of renal cell carcinoma. We hypothesize motor coordination errors will correlate with total errors and provide validity evidence for error tolerance as a performance metric. Treatment with actinomycin D abolished CdCl2-induced elevation of SGK1 mRNA level.

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This study successfully transformed human MSCs to OS-like cells by Rb knockdown and c-Myc overexpression that may be a useful platform for further investigation of preventive and target therapy for human OS. While the degree of mandibular protrusion created by the MAS affects the dimensions of the upper airway, the degree of the vertical opening exerts no significant dimensional effect in the sagittal plane in fully dentate apneic patients. The studies supporting the use of degarelix are criticized on the basis of selection bias in regards to the heterogeneous populations described, ad hoc analyses with low statistical merit, and the presentation of selected data that would appear to be favorable to the evaluated medication. Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family.

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It should be based on underlying pathophysiology, especially the duration of hyponatraemia (acute vs. Cross-Coupling of Aryl Halides and Allyl Acetates with Arylboron Reagents in Water Using an Amphiphilic Resin-Supported Palladium Catalyst.

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Data on complementary feeding practices, including the age of initiation, the type of foods eaten, the frequency of food intake and the reasons for starting complementary feeding, were collected. Here we report that the SAE2 subunit of human SUMO activation enzyme (SAE) underwent rapid nucleocytoplasmic shuttling and its nuclear accumulation depended on SUMO modification at the C terminus.

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A case of harvest-mite infestation acquired in the South Lakeland area is described in a 7-year-old boy and his immediate family. Porcine Epidemic Diarrhea Virus Infection Induced the Unbalance of Gut Microbiota in Piglets. Methemoglobin-forming effect and its role in the mechanism of action of a number of benzo-2,1,3-thiadiazole class radioprotective agents

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Fine needle aspiration (FNA) cytologic diagnosis of toxoplasmic lymphadenitis with demonstration of a tissue cyst containing bradyzoites has been very rarely reported. The resurgence and genetic implications of New World primates in biomedical research. The study was conducted from October 2014 to January 2015, based on the revised World Health Organization protocol of 2009 for surveillance of antimalarial drug therapeutic efficacy study. Fasting adiponectin, insulin, glucose, and revised homeostatic model assessment of insulin resistance. Use of equivocal zone in interpretation of results of the amplified mycobacterium tuberculosis direct test for diagnosis of tuberculosis.

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Use of a mammalian internal ribosomal entry site element for expression of a foreign protein by a transfectant influenza virus. Three-dimensional remodeling of cardiomyocytes in a patient with aortic stenosis: scanning electron microscopy.

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Since EGF can induce both PKC activation and cell proliferation, and because PKC activation requires membrane-derived phospholipids and diacylglycerol, these data suggest that specific fatty acid modulation of mammary epithelial cell mitogenesis is mediated through alterations in PKC alpha activation. Although hearing acuity declines with aging in everybody, the variation in hearing thresholds is large. The in vitro performance of the PAMAM dendron-PLL polyplexes was controlled by the balance of cellular uptake and endosomal escape by a buffering effect. To elicit infected hip arthroplasty preferences from outpatients and surgeons using time trade-off method based on a paper-based survey.