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Ectopic expression of RXR alpha LBD fragment in cells that do not have a detectable endogenous RXR alpha LBD fragment, blocked synergistic radiosensitizing action of RA, as determined by growth inhibition, cell death and colony formation assays. There is a strong correlation between apoptosis and the host protein translation machinery: the pathogen makes all possible efforts to modify this process so as to inhibit cell suicide and ensure that it can survive and, in some cases, establish latent infection. To perform the original phase I/II trial of autologous platelet tissue graft in gynecologic surgery to evaluate toxicity and efficacy on decreasing pain. Grape seed extract improves epithelial structure and suppresses inflammation in ileum of IL-10-deficient mice. The new model couples a cardiovascular hemodynamics function model with an explicit account of the LV wall thickness variation and a long-term renal system model.

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Pericardial adipose tissue, atherosclerosis, and cardiovascular disease risk factors: the Jackson heart study. This loss of inhibitory drive allows the activation of excitatory feedback loops, leading to repetitive, synchronous firing of large groups of neurons. The ability to integrate information from multiple sensory modalities is crucial to the survival of organisms living in complex environments.

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Use of the critical incident technique in the development of a measurement tool for satisfaction in psychiatry Seropositivity for human T-lymphotropic virus types I and II among donors at the Municipal Blood Bank of Caracas and associated risk factors Misinformed consent: an enigma in modern social science research. Foker and accomplished early repair in 3 infants with long gap atresia. Effects of prostacyclin analogue (carbacyclin) on the interaction of platelets with different collagen substrates.

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journal articles, books and online literature was reviewed to investigate faculty development programmes in surgery. Improved psoriasis with weight loss: the role of behavioural factors. Although the small sample size may have limited the ability to detect metabolic effects on longevity in this study, the general approach may be broadly applicable to examinations of metabolic aging in humans. A class of such waveguides is found from a relation between two spectral problems.

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Effectiveness of varicella vaccine in children infected with HIV. The use of visible light-cured (VLC) resin was evaluated in contrast to more traditional chemical-cured resins for reconstruction of the spine in experimental rats. High affinity antibodies to cobrotoxin were obtained by immunization with derivatives of glutaraldehyde (GA)-modified cobrotoxin. Neutralization with specific anti-TGF-beta1 antibody showed decreased expression of MMP-9, indicating that TGF-beta controls the baseline MMP-9 expression by a direct autocrine mechanism.

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To systematically review the evidence for the impact of study design and setting on the interpretation of tuberculosis (TB) transmission using clustering derived from Mycobacterial Interspersed Repetitive Units-Variable Number Tandem Repeats (MIRU-VNTR) strain typing. Antibody against these viruses was demonstrated by immune electron microscopy in all of 7 convalescent phase sera but in none of 11 acute phase sera collected. Antibiotics are used routinely in the postoperative care of functional endoscopic sinus surgery (FESS), but their efficacy has not been well evaluated. Biphasic plasticity of dendritic fields in layer V motor neurons in response to motor learning.

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Although the overall survival rate increased over the observation period in both age groups, the older study group was characterized by shorter disease-free survival. Re: risk of myocardial infarction in older men receiving testosterone therapy. In contrast to atrial remodeling, electrical remodeling in the ventricle can result in prolonged APD (with altered activation sequence) or reversal of APD gradient orientation (with rapid rate), suggesting that the nature of ventricular electrical remodeling induced by these two perturbations is different. Protective effects of quercetin and hyperoside on renal fibrosis in rats with unilateral ureteral obstruction.

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The translation of the mRNA encoding the Ubiquitin-Specific Peptidase 1 (USP1), a Ubiquitin peptidase with important function in multiple DNA repair pathways, is inhibited by CDDP exposure in the sensitive cells, but not in the resistant cells. Determination of niobium in rocks, ores and alloys by atomic-absorption spectrophotometry. The hybridization detection was accomplished by using methylene blue (MB), an electroactive lable, as the indicator.

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We evaluated algorithm performance for all possible combinations of selected characteristics using an iterative approach. By using the last two techniques, data have been collected from small areas of the samples. During resolution, lipoxin A4, resolvin (Rv) D1 and RvD2, protectin D1 (PD1), and maresin 1 (MaR1) were transiently produced while RvD5 was continually generated. However, few studies have examined the mechanisms underlying sensitization to ethanol.

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The Cochrane Database of systematic reviews was searched for meta-analyses of randomized controlled studies comparing exercise or analgesics with a control group (placebo or usual care) and with pain as an outcome. Transient changes of T-wave pattern may occur in athletes as an effect of athletic conditioning, without changes of cardiac dimension or alteration of indexes of LV function. The response of the IGFBP-3 to the hGH applications was lower in comparison to IGF-I. This study showed a relation between PMS and equol-production status in Japanese women. The ability of each deletion derivative to excise was measured by whether or not kanamycin-resistant tobacco calli were recovered.

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The series included 120 patients with large unresectable hepatocellular carcinoma lesions, the largest of which were greater than 3 cm in largest dimension. In the visual system, these patterns include retinotopic organization and the segregation of individual axons onto different subsets of target neurons based on the eye of origin (ocular dominance) or receptive field type (ON or OFF).

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The calculations are performed for systems consisting of one to three monomer units and are found to reproduce reasonably the experimental spectral features. Software elements are described in terms of system programming features required for creating and incorporating the desired logic sequencing into analytical instrumentation. The objective was to gain a deeper understanding of how individuals with experiences of being on sick leave perceive their encounters with professionals, and how such encounters affected their ability to return to work, as well as their attitudes towards the sickness insurance system.

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Gestational diabetes hinders expressive language in offspring into middle childhood. Furthermore, this change in muscle metabolism is likely to be dissociated from fat deposition and beef quality, providing new criteria for genetic selection in favour of muscle growth. Determination of surface and interface magnetic properties for the multiferroic heterostructure Co/BaTiO3 using spleed and arpes. Knockdown of Ubc13 from Tregs converted the Tregs to effector T cells. The drug was given by intravenous infusion 3 times per week for 2 weeks, twice per week for the next 2 weeks, and then weekly.

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A thorough knowledge and understanding of available and emerging treatment options for neurogenic detrusor overactivity is paramount to assisting clinicians in choosing an appropriate treatment. To review the options for the treatment of chronic pelvic pain in adolescents with endometriosis. Disruption of either the p14ARF- mdm2- p53 or p16INK4A- Rb1 pathways produces a breakdown of regulatory mechanisms and creates a gateway for tumorigenesis. Oral administration of the angiotensin converting enzyme inhibitor CGS 16617 significantly lowered mean arterial pressure. Multiple logistic regression analysis showed that the existence of periodontitis was associated positively with age, the Brinkman index, systolic blood pressure, number of white blood cells, feeling of irritation, and negatively with the use of interdental cleaners.

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Perceptual localization of visual stimuli flashed during saccades. Sustained bundle branch reentry as a mechanism of clinical tachycardia. Findings reveal multi-level benefits of social support group participation at intrapersonal (self-acceptance, improved mental health), interpersonal (reduced isolation, friendships), community (reciprocity, reduced stigma and discrimination), and structural (housing, employment, immigration, health care) levels. A sulfur compound, bis(4-hydroxybenzyl)sulfide (1) was isolated from the root extract of Pleuropterus ciliinervis. To investigate chemokine expression networks in chronic hepatitis C virus (HCV) infection, we used microarray analysis to determine chemokine expression in human infection and in chimpanzees experimentally infected with HCV.

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Naphthaldehydes as reversible inhibitors of rat hepatic aryl sulfotransferase IV (tyrosine-ester sulfotransferase). We previously reported that plasma Lp-PLA2 was associated with aortic valve disease progression and degeneration of bioprostheses. The primary objective of this research was to model and understand the chelate-modified Fenton reaction for the destruction of trichloroethylene (TCE) present in both the aqueous and organic (in the form of droplets) phases. In this group, SACE levels were higher in men than in women (p less than 0.02). A case is reported of a 5-month-old child who developed subcutaneous emphysema and pneumomediastinum following the application of external pressure on the trachea during intubation using a non-kinkable tube with a stylet in situ.

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The radical pterygomaxillotomy approach is used for gaining access to chordomas of the upper half of the clivus, with or without lateral extension. In addition, we analyzed the effect of attenuation of p53 function, via the p53 inhibitor pifithrin-alpha, and knockdown of p53 mRNA on the cytotoxicity of microcystin-LR using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Pathway analysis identified enrichment of non-synonymous variants in genes responsible for cell assembly and organization, cell morphology, and cell function and maintenance.

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Purification and characterization of an extracellular beta-xylosidase from a newly isolated Fusarium verticillioides. Potential preventive and therapeutic approaches toward it include inhibition of AGE formation, breakage of preformed AGE-proteins crosslinks, blockade of AGE-RAGE interactions with RAGE competitors or antagonists and RAGE-specific signaling inhibition. Retrospective analysis was performed of 10 shoulder MR studies of 10 patients older than 25 years with os acromiale.

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A Phase II clinical trial was conducted in 30 women with metastatic breast cancer in whom piroxantrone was administered at a dose of 160 mg/m2 by 1-hour infusion. Electrical control of a long-lived spin qubit in a Si/SiGe quantum dot. We defined six risk subgroups, based on admission laboratory data and examined the frequency of 30-day in-hospital mortality within these subgroups. Ultrasound detection of pneumoperitoneum based on typical ultrasound morphology We addressed this research gap by describing 8 dimensions of health-related quality of life (HRQOL) for antineutrophil cytoplasmic antibody-associated vasculitis (AAV) patients and their spouses and compared patients and spouses with norms for the general US population.

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The yeast Cryptococcus albidus isolated from the leaves of maize (strain 1003) and cucumbers (strain 1014) produce the capsule substances which can protect the tobacco and datura plants from tobacco mosaic virus. The purpose of this study was to examine the volumetric differences in the brain of IL-6 overexpressing mice and compare with corresponding control mice using magnetic resonance imaging.

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A prospective study on the Malaysian population is a high priority to confirm these findings. A systematic review and meta-analysis of clinical and patient-reported outcomes following two procedures for recurrent traumatic anterior instability of the shoulder: Latarjet procedure vs.